Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer.

Product information

CAS Number: 516-05-2

Molecular Weight: 118.09

Formula: C4H6O4

Chemical Name: 2-methylpropanedioic acid

Smiles: CC(C(O)=O)C(O)=O

InChiKey: ZIYVHBGGAOATLY-UHFFFAOYSA-N

InChi: InChI=1S/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (846.81 mM; Need ultrasonic). H2O : 100 mg/mL (846.81 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Vitamin B-12 is required for Methylmalonate (Methylmalonic acid; MMA) to be converted to succinyl-CoA, and in combination with folic acid, for homocysteine (HC) to be converted to methionine. Therefore, Methylmalonate is clearly more specific to vitamin B-12 deficiency compared to HC.

Products are for research use only. Not for human use.